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DeCS
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Descriptor English:
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Promyelocytic Leukemia Zinc Finger Protein
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Descriptor Spanish:
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Proteína de la Leucemia Promielocítica con Dedos de Zinc
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Descriptor Portuguese:
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Proteína com Dedos de Zinco da Leucemia Promielocítica
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Synonyms English:
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PLZF Protein
Promyelocytic Leukaemia Zinc Finger Protein
ZBTB16 Protein
Zinc Finger and BTB Domain Containing 16 Protein
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Tree Number:
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D12.776.260.522.625
D12.776.930.375.625
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Definition English:
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A Kruppel-type transcription factor consisting of an N-terminal BTB DOMAIN and nine CYS2-HIS2 ZINC FINGERS. It localizes to the nucleus and regulates cell cycle progression and gene expression for tissue development and homeostasis; it may also function as an epigenetic regulator through its interactions with HISTONE DEACETYLASE. Genetic rearrangements involving the ZBTB16 gene are associated with ACUTE PROMYELOCYTIC LEUKEMIA. |
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History Note English:
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2018
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Allowable Qualifiers English:
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Record Number:
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57115
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Unique Identifier:
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D000075722
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Occurrence in VHL:
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Similar:
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DeCS
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